Whole transcriptome sequencing identifies increasedCXCR2expression in PNH granulocytes
Author:
Affiliation:
1. Hematology Branch; National Heart, Lung, and Blood Institute (NHLBI); NIH; Bethesda MD USA
2. BGI-Shenzhen; Shenzhen China
3. Trans-NIH Center for Human Immunology; Autoimmunity; and Inflammation; NIH; Bethesda MD USA
Funder
National Institutes of Health
National Heart, Lung, and Blood Institute
The Aplastic Anemia & MDS International Foundation
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjh.14502/fullpdf
Reference15 articles.
1. MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment;Bernhagen;Nature Medicine,2007
2. Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in ‘normal’ phenotype cells;Chen;Leukemia,2005
3. CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow;Eash;The Journal of Clinical Investigation,2010
4. CD14 deficiency leads to increased MIP-2 production, CXCR2 expression, neutrophil transmigration, and early death in pneumococcal infection;Echchannaoui;Journal of Leukocyte Biology,2005
5. Circulating primitive stem cells in paroxysmal nocturnal hemoglobinuria (PNH) are predominantly normal in phenotype but granulocyte colony-stimulating factor treatment mobilizes mainly PNH stem cells;Johnson;Blood,1998
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