Early or deferred initiation of efavirenz during rifampicin‐based TB therapy has no significant effect on CYP3A induction in TB‐HIV infected patients

Author:

Aklillu Eleni1ORCID,Zumla Alimuddin23,Habtewold Abiy4,Amogne Wondwossen5,Makonnen Eyasu6,Yimer Getnet6,Burhenne Jürgen7,Diczfalusy Ulf8

Affiliation:

1. Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital Huddinge C1:68 Karolinska Institutet Stockholm Sweden

2. Division of Infection and Immunity University College London, NIHR Biomedical Research Centre at UCL Hospitals NHS Foundation Trust London UK

3. UNZA‐UCLMS Research and Training Program, Department of Medicine University Teaching Hospital Lusaka Zambia

4. Department of Pharmaceutical Sciences, School of Pharmacy William Carey University Biloxi MS USA

5. Department of Internal Medicine, College of Health Science Addis Ababa University Addis Ababa Ethiopia

6. Department of Pharmacology, College of Health Sciences Addis Ababa University Addis Ababa Ethiopia

7. Department of Clinical Pharmacology and Pharmacoepidemiology University of Heidelberg Heidelberg Germany

8. Division of Clinical Chemistry, Department of Laboratory Medicine Karolinska Institutet at Karolinska University Hospital Stockholm Sweden

Funder

European and Developing Countries Clinical Trials Partnership

Vetenskapsrådet

Publisher

Wiley

Subject

Pharmacology

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