Variability in plasma rifampicin concentrations and role of SLCO1B1 , ABCB1 , AADAC2 and CES2 genotypes in Ethiopian patients with tuberculosis

Author:

Sileshi Tesemma12,Makonnen Eyasu23,Telele Nigus Fikrie4,Barclay Victoria4,Zumla Alimuddin5,Aklillu Eleni6

Affiliation:

1. Department of Pharmacy, Ambo University, Ambo, Ethiopia

2. Department of Pharmacology and Clinical Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia

3. Center for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia

4. Department of Laboratory Medicines, Karolinska Institutet, Stockholm, Sweden

5. Department of Infection, Division of Infection and Immunity, University College London; NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, UK

6. Department of Global Public Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

Funder

Fogarty International Centre

National Institute of Allergy and Infectious Disease of the National Institute of Health

Centre of Innovative Drug Development and Therapeutic Trial for Africa (CDT-Africa), Addis Ababa University

The European & Developing Countries Clinical Trials Partnership

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,General Medicine

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