Mepolizumab decreases tissue eosinophils while increasing type‐2 cytokines in eosinophilic chronic rhinosinusitis

Author:

Walter Sophie1ORCID,Ho Jacqueline12,Alvarado Raquel1,Smith Greg3,Croucher David R.24,Liang Sharron5,Grayson Jessica W.16,Mangussi‐Gomes João1,Van Es Simone L.37,Earls Peter15,Rimmer Janet189,Campbell Raewyn11011,Kalish Larry11213,Sacks Raymond1111213,Harvey Richard J.111

Affiliation:

1. Rhinology and Skull Base Research Group St Vincent’s Centre for Applied Medical Research University of New South Wales Sydney Australia

2. St Vincent’s Clinical School Faculty of Medicine University of New South Wales Sydney Australia

3. School of Medical Sciences University of New South Wales Sydney Australia

4. Garvan Institute of Medical Research Sydney New South Wales Australia

5. Department of Anatomical Pathology St Vincent’s Hospital Sydney Australia

6. Department of Otolaryngology‐Head and Neck Surgery University of Alabama at Birmingham Birmingham UK

7. New South Wales Health Education and Training Institute Sydney Australia

8. Woolcock Institute University of Sydney Sydney Australia

9. Faculty of Medicine Notre Dame University Sydney Australia

10. Department of Otolaryngology Head and Neck Surgery Royal Prince Alfred Hospital Sydney Australia

11. Faculty of Medicine and Health Sciences Macquarie University Sydney Australia

12. Department of Otolaryngology, Head and Neck Surgery Concord General Hospital University of Sydney Sydney Australia

13. Faculty of Medicine University of Sydney Sydney Australia

Funder

GlaxoSmithKline

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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