Long‐term immune response accompanies clinical outcomes in severe asthmatics treated with anti‐IL‐5/IL‐5R biologics

Author:

Lorente‐Sorolla C.1ORCID,Bernaola J.2,Sánchez‐Mellado D.3,Gil‐Martínez M.14ORCID,Naharro‐González S.1ORCID,Betancor D.2ORCID,Fernández‐Nieto M.2,Pinillos‐Robles E. J.3ORCID,Santillán Coello J. M.5,Villacampa‐Aubá J. M.5ORCID,Rodríguez‐Nieto M. J.3ORCID,Sastre J.24ORCID,Valverde‐Monge M.24ORCID,Rodrigo‐Muñoz J. M.14ORCID,del Pozo V.146ORCID

Affiliation:

1. Immunoallergy Laboratory, Department of Immunology Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS‐FJD, UAM) Madrid Spain

2. Allergy Unit Hospital Universitario Fundación Jiménez Díaz Madrid Spain

3. Pulmonology Unit Hospital Universitario Fundación Jiménez Díaz Madrid Spain

4. CIBER de Enfermedades Respiratorias (CIBERES) Instituto de Salud Carlos III (ISCIII) Madrid Spain

5. Department of ENT and Cervicofacial Surgery Fundación Jiménez Díaz University Hospital Madrid Spain

6. Universidad Autónoma de Madrid Madrid Spain

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference11 articles.

1. A pragmatic guide to choosing biologic therapies in severe asthma

2. GINA Main Report.Global Initiative for Asthma ‐ GINA.2023https://ginasthma.org/2023‐gina‐main‐report/

3. Eosinophilic inflammation: an appealing target for pharmacologic treatments in severe asthma;Vatrella A;Biomedicine,2022

4. Interleukins 4 and 13 in Asthma: Key Pathophysiologic Cytokines and Druggable Molecular Targets

5. Mepolizumab decreases tissue eosinophils while increasing type‐2 cytokines in eosinophilic chronic rhinosinusitis

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