Affiliation:
1. Department of Diabetes, Endocrinology, Diabetes and Metabolism Kitasato University, School of Medicine Sagamihara Japan
2. Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation Gunma University Maebashi Japan
Abstract
AbstractFew studies in Asian populations have analyzed how glucagon secretion is affected by ingested glucose, proteins or lipids, individually. To investigate the fluctuations of glucagon secretion after the intake of each of these nutrients, 10 healthy volunteers underwent oral loading tests using each of glucose, proteins and lipids, and blood levels of glucose, insulin and glucagon were measured every 30 min for 120 min. Whereas glucagon secretion was suppressed and minimally affected by oral glucose intake and lipid intake, respectively, oral protein intake robustly increased glucagon secretion, as well as insulin secretion. Further studies are needed to elucidate the mechanism by which protein loading increases glucagon secretion.
Subject
General Medicine,Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
1 articles.
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