Altered intestinal antibacterial gene expression response profile in irritable bowel syndrome is linked to bacterial composition and immune activation

Author:

Bennet Sean M. P.12ORCID,Sundin Johanna12ORCID,Magnusson Maria K.2ORCID,Strid Hans3ORCID,Tap Julien4ORCID,Derrien Muriel4ORCID,Le Nevé Boris4ORCID,Doré Joël5,Törnblom Hans16ORCID,Simrén Magnus167ORCID,Öhman Lena12ORCID

Affiliation:

1. Institute of Medicine; University of Gothenburg; Gothenburg Sweden

2. Institute of Biomedicine; University of Gothenburg; Gothenburg Sweden

3. Department of Internal Medicine; Södra Älvsborg Hospital; Borås Sweden

4. Danone Nutricia Research; Palaiseau France

5. French National Institute for Agricultural Research (INRA) MetaGenoPolis; Jouy-en-Josas France

6. Centre for Person-Centred Care; University of Gothenburg; Gothenburg Sweden

7. Center for Functional Gastrointestinal and Motility Disorders; University of North Carolina; Chapel Hill North Carolina

Funder

Medicinska Forskningsrådet

Publisher

Wiley

Subject

Gastroenterology,Endocrine and Autonomic Systems,Physiology

Reference46 articles.

1. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis;Lovell;Clin Gastroenterol Hepatol,2012

2. Bowel disorders;Lacy;Gastroenterology,2016

3. Gut microbiota as potential orchestrators of irritable bowel syndrome;Bennet;Gut Liv,2015

4. Role of toll like receptors in irritable bowel syndrome: differential mucosal immune activation according to the disease subtype;Belmonte;PLoS One,2012

5. Crosstalk at the mucosal border: importance of the gut microenvironment in IBS;Ohman;Nat Rev Gastroenterol Hepatol,2015

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