A new, broad-spectrum azole antifungal: posaconazole ? mechanisms of action and resistance, spectrum of activity
Author:
Publisher
Wiley
Subject
Infectious Diseases,Dermatology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1439-0507.2006.01295.x/fullpdf
Reference20 articles.
1. An update on antifungal targets and mechanisms of resistance inCandidaalbicans
2. Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds
3. Three-Dimensional Models of Wild-Type and Mutated Forms of Cytochrome P450 14α-Sterol Demethylases from Aspergillus fumigatus and Candida albicans Provide Insights into Posaconazole Binding
4. Contribution of mutations in the cytochrome P450 14α-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans
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