Semi-mechanistic pharmacokinetic/pharmacodynamic modelling of the antimalarial effect of artemisinin
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.2005.02508.x/fullpdf
Reference32 articles.
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2. Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults;Ashton;Drug Metab Dispos,1998
3. Clinical efficacy and pharmacokinetics of artemisinin monotherapy and in combination with mefloquine in patients with falciparum malaria;Alin;Br J Clin Pharmacol,1996
4. Artemisinin kinetics and dynamics during oral and rectal treatment of uncomplicated malaria;Ashton;Clin Pharmacol Ther,1998
5. A semi-physiological pharmacokinetic model for artemisinin in healthy subjects incorporating autoinduction of metabolism and saturable first-pass hepatic extraction;Gordi;Br J Clin Pharmacol,2005
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