Formation and elimination of sulphamethoxazole hydroxylamine after oral administration of sulphamethoxazole.
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.1994.tb04339.x/fullpdf
Reference16 articles.
1. Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome;Gordin;Ann int Med,1984
2. Synthesis and in vitro toxicity of hydroxylamine metabolites of sulfonamides;Rieder;J Pharmac exp Ther,1988
3. Diagnosis of sulfonamide hypersensitivity reactions by in vitro‘rechallenge’ with hydroxylamine metabolites;Rieder;Ann int Med,1989
4. In vitro evaluation of a toxic metabolite of sulfadiazine;Shear;Can J Physiol Pharmac,1985
5. Differences in metabolism of sulfonamides predisposing to idiosyncratic toxicity;Shear;Ann int Med,1986
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