Mercaptopurine in childhood leukaemia: the effects of dose escalation on thioguanine nucleotide metabolites
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.1996.tb00021.x/fullpdf
Reference6 articles.
1. Mercaptopurine metabolism and risk of relapse in childhood lymphoblastic leukaemia
2. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
3. Intensification of treatment and survival in all children with lymphoblastic leukaemia: results of UK Medical Research Council trial UKALL X
4. 6-Mercaptopurine dose escalation and its effect on drug tolerance in childhood lymphoblastic leukaemia
5. High-performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample
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2. Differential effects of thiopurine methyltransferase (TPMT) and multidrug resistance-associated protein gene 4 (MRP4) on mercaptopurine toxicity;Cancer Chemotherapy and Pharmacology;2017-06-16
3. Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait;Clinical Pharmacology & Therapeutics;2016-11-18
4. The pharmacogenetic basis of individual variation in thiopurine metabolism;Personalized Medicine;2012-09
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