Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait-Reference-Cited by-同舟云学术

Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait

Published:2016-11-18 Issue:3 Volume:101 Page:373-381
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Liu C¹,Yang W¹,Pei D²,Cheng C²,Smith C¹,Landier W³,Hageman L³,Chen Y³,Yang JJ¹,Crews KR¹,Kornegay N¹,Karol SE⁴,Wong FL⁵,Jeha S⁴,Sandlund JT⁴,Ribeiro RC⁴,Rubnitz JE⁴,Metzger ML⁴,Pui C-H⁴,Evans WE¹,Bhatia S³,Relling MV¹

Affiliation:

1. Department of Pharmaceutical Sciences; St. Jude Children's Research Hospital; Memphis Tennessee USA

2. Department of Biostatistics; St. Jude Children's Research Hospital; Memphis Tennessee USA

3. School of Medicine; University of Alabama at Birmingham; Birmingham Alabama USA

4. Department of Oncology; St. Jude Children's Research Hospital; Memphis Tennessee USA

5. Department of Population Sciences; City of Hope; Duarte California USA

Funder

Children's Oncology Group Chair's grant

Children's Oncology Group Statistical Center

Children's Oncology Group Specimen Banking

The National Cancer Institute

the American Lebanese Syrian Associated Charities

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference55 articles.

1. Thiopurine methyltransferase in acute lymphoblastic leukemia;Relling;Blood,2006

2. Thiopurine treatment in inflammatory bowel disease: clinical pharmacology and implication of pharmacogenetically guided dosing;Teml;Clin. Pharmacokinet.,2007

3. Preventing toxicity with a gene test;Marshall;Science,2003

4. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus;Relling;J. Natl. Cancer Inst.,1999

5. Analysis of thiopurine methyltransferase variant alleles in childhood acute lymphoblastic leukaemia;McLeod;Br. J. Haematol.,1999

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