The decline of anti-drug antibody titres after discontinuation of anti-TNFs: implications for predicting re-induction outcome in IBD-Reference-Cited by-同舟云学术

The decline of anti-drug antibody titres after discontinuation of anti-TNFs: implications for predicting re-induction outcome in IBD

Published:2012-01-30 Issue:6 Volume:35 Page:714-722
ISSN:0269-2813
Container-title:Alimentary Pharmacology & Therapeutics
language:en
Short-container-title:Letters to the Editors

Author:

Ben-Horin S.¹,Mazor Y.²,Yanai H.³,Ron Y.³,Kopylov U.¹,Yavzori M.¹,Picard O.¹,Fudim E.¹,Maor Y.¹,Lahat A.¹,Coscas D.¹,Eliakim R.¹,Dotan I.³,Chowers Y.²

Affiliation:

1. Department of Gastroenterology; Sheba Medical Center & Sackler School of Medicine; Tel-Aviv University; Israel

2. Rambam Health Care Campus & Bruce Rappaport School of Medicine; Technion Israel Institute of Technology; Haifa; Israel

3. Department of Gastroenterology and Liver Diseases; IBD Center; Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine; Tel Aviv University; Israel

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2036.2012.04997.x/fullpdf

Reference24 articles.

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3. The immunogenic part of infliximab is the F(ab’)2 fragment, but measuring antibodies to the intact infliximab molecule is more clinically useful;Ben-Horin;Gut,2011

4. Tumor necrosis factor-alpha binding capacity and anti-Infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of Infliximab in Crohn's disease;Ainsworth;Am J Gastroenterol,2008

5. Influence of trough serum levels and immunogenicity on long-term outcome of adalimumab therapy in Crohn's disease;Karmiris;Gastroenterology,2009

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