5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes

Author:

Pardini Barbara,Kumar Rajiv,Naccarati Alessio,Novotny Jan,Prasad Rashmi B.,Forsti Asta,Hemminki Kari,Vodicka Pavel,Lorenzo Bermejo Justo

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference11 articles.

1. 5-fluorouracil: mechanisms of action and clinical strategies;Longley;Nat Rev Cancer,2003

2. MTHFR polymorphisms and 5-FU-based adjuvant chemotherapy in colorectal cancer;Afzal;Ann Oncol,2009

3. Resistance to fluorodeoxyuridine-induced DNA damage and cytotoxicity correlates with an elevation of deoxyuridine triphosphatase activity and failure to accumulate deoxyuridine triphosphate;Canman;Cancer Res,1993

4. Variations in patterns of DNA damage induced in human colorectal tumor cells by 5-fluorodeoxyuridine: implications for mechanisms of resistance and cytotoxicity;Canman;Proc Natl Acad Sci USA,1992

5. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer;de Gramont;J Clin Oncol,2000

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