Nonparametric population modeling of valproate pharmacokinetics in epileptic patients using routine serum monitoring data: implications for dosage
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2710.2003.00538.x/fullpdf
Reference39 articles.
1. A Review of Pharmacodynamics and Pharmacokinetics in Seizure Management
2. Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action
3. Disposition of valproic acid in man
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1. Physiologically based mechanistic insight into differential risk of valproate hepatotoxicity between children and adults: A focus on ontogeny impact;CPT: Pharmacometrics & Systems Pharmacology;2023-10-11
2. Effect of CYP2C19, UGT1A8, and UGT2B7 on valproic acid clearance in children with epilepsy: a population pharmacokinetic model;European Journal of Clinical Pharmacology;2018-04-17
3. A population pharmacokinetic model taking into account protein binding for the sustained-release granule formulation of valproic acid in children with epilepsy;European Journal of Clinical Pharmacology;2018-03-21
4. Population Pharmacokinetics of Valproic Acid in Patients with Mania: Implication for Individualized Dosing Regimens;Clinical Therapeutics;2017-06
5. Individualizing Antiepileptic Therapy for Patients;Individualized Drug Therapy for Patients;2017
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