Single and multiple dose intravenous and oral pharmacokinetics of the hedgehog pathway inhibitor vismodegib in healthy female subjects-Reference-Cited by-同舟云学术

Single and multiple dose intravenous and oral pharmacokinetics of the hedgehog pathway inhibitor vismodegib in healthy female subjects

Published:2012-10-09 Issue:5 Volume:74 Page:788-796
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:

Author:

Graham Richard A.,Hop Cornelis E. C. A.,Borin Marie T.,Lum Bert L.,Colburn Dawn,Chang Ilsung,Shin Young G.,Malhi Vikram,Low Jennifer A.,Dresser Mark J.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.2012.04281.x/fullpdf

Reference19 articles.

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2. Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449;Rudin;N Engl J Med,2009

3. Inhibition of the hedgehog pathway in advanced basal-cell carcinoma;Von Hoff;N Engl J Med,2009

4. A pivotal study evaluating efficacy and safety of the hedgehog pathway inhibitor (HPI) vismodegib (GDC-0449) in patients with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC);Sekulic;Melanoma Res,2011

5. Determination of GDC-0449, a small-molecule inhibitor of the hedgehog signaling pathway, in human plasma by solid phase extraction-liquid chromatographic-tandem mass spectrometry;Ding;J Chromatogr B Analyt Technol Biomed Life Sci,2010

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