Determination of GDC-0449, a small-molecule inhibitor of the Hedgehog signaling pathway, in human plasma by solid phase extraction-liquid chromatographic-tandem mass spectrometry-Reference-Cited by-同舟云学术

Determination of GDC-0449, a small-molecule inhibitor of the Hedgehog signaling pathway, in human plasma by solid phase extraction-liquid chromatographic-tandem mass spectrometry

Published:2010-03 Issue:9-10 Volume:878 Page:785-790
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Ding X.,Chou B.,Graham R.A.,Cheeti S.,Percey S.,Matassa L.C.,Reuschel S.A.,Meng M.,Liu S.,Voelker T.,Lum B.L.,Rudewicz P.J.,Hop C.E.C.A.

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference6 articles.

1. Inhibition of Smoothened Signaling Prevents Ultraviolet B-Induced Basal Cell Carcinomas through Regulation of Fas Expression and Apoptosis

2. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1+/−p53−/− mice

3. A paracrine requirement for hedgehog signalling in cancer

4. Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

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