A Strategy for Selective O6-Alkylguanine-DNA Alkyltransferase Depletion Under Hypoxic Conditions-Reference-Cited by-同舟云学术

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A Strategy for Selective O6-Alkylguanine-DNA Alkyltransferase Depletion Under Hypoxic Conditions

Published:2012-05-23 Issue:2 Volume:80 Page:279-290
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:

Author:

Penketh Philip G.,Shyam Krishnamurthy,Baumann Raymond P.,Ishiguro Kimiko,Patridge Eric V.,Zhu Rui,Sartorelli Alan C.

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference39 articles.

1. Clinical relevance of MGMT in the treatment of cancer;Gerson;J Clin Oncol,2002

2. Isolation and purification of O6-alkylguanine-DNA alkyltransferase from human leukemic cells. Prevention of chloroethylnitrosourea-induced cross-links by purified enzyme;Brent;Pharmacol Ther,1985

3. Inactivation of AGT involved in extracellular signal pathway to regulate cell proliferation;Yan;Proc Am Assoc Cancer Res,2004

4. Active-site alkylation destabilizes human O6-alkylguanine DNA alkyltransferase;Rasimas;Protein Sci,2004

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1. Novel Hypoxia-Associated Gene Signature Depicts Tumor Immune Microenvironment and Predicts Prognosis of Colon Cancer Patients;Frontiers in Genetics;2022-06-06

2. Significance of Specific Oxidoreductases in the Design of Hypoxia-Activated Prodrugs and Fluorescent Turn off–on Probes for Hypoxia Imaging;Cancers;2022-05-29

3. Therapeutic targeting of the hypoxic tumour microenvironment;Nature Reviews Clinical Oncology;2021-07-29

4. Physicochemical Considerations of Tumor Selective Drug Delivery and Activity Confinement with Particular Reference to 1,2-Bis(Sulfonyl)-1- Alkylhydrazines Delivery;Current Drug Delivery;2020-07-31

5. Reductive Activity and Mechanism of Hypoxia- Targeted AGT Inhibitors: An Experimental and Theoretical Investigation;International Journal of Molecular Sciences;2019-12-13

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