Isolation and purification of O6-Alkylguanine-DNA alkyltransferase from human leukemic cells. Prevention of chloroethylnitrosourea-induced cross-links by purified enzyme

Author:

Brent Thomas P.

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmacology

Reference47 articles.

1. Covalent attachment of DNA to agarose: Improved synthesis and use in affinity chromatography;Arndt-Jovin;Eur. J. Biochem.,1975

2. Repair of O6-(2-chloroethy)guanine mediates the biological effects of chloroethlnitrosoureas;Bodell;Environ. Health Perspect.,1985

3. A system in mouse liver for repair of O6-methylguanine lesions in methylated DNA;Bogden;Nucleic Acids Res.,1981

4. Suppression of cross-link formation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts;Brent;Cancer Res.,1984

5. Inactivation of purified human O6-alkylguanine-DNA alkyltransferase by alkylating agents and alkylated DNA;Brent;Cancer Res.,1986

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