Inhibitors Incorporating Zinc‐Binding Groups Target the GlcNAc‐PI de‐N‐acetylase inTrypanosoma brucei, the Causative Agent of African Sleeping Sickness-Reference-Cited by-同舟云学术

Inhibitors Incorporating Zinc‐Binding Groups Target the GlcNAc‐PI de‐N‐acetylase inTrypanosoma brucei, the Causative Agent of African Sleeping Sickness

Published:2012-01-19 Issue:3 Volume:79 Page:270-278
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chemical Biology & Drug Design

Author:

Abdelwahab Nuha Z.¹,Crossman Arthur T.¹,Sullivan Lauren¹,Ferguson Michael A. J.¹,Urbaniak Michael D.

Affiliation:

1. Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1747-0285.2011.01300.x

Reference36 articles.

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2. Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

3. Cloning of Trypanosoma brucei and Leishmania major Genes Encoding the GlcNAc-Phosphatidylinositol De-N-acetylase of Glycosylphosphatidylinositol Biosynthesis That Is Essential to the African Sleeping Sickness Parasite

4. Essential Roles for GPI-anchored Proteins in African Trypanosomes Revealed Using Mutants Deficient in GPI8

5. Chemical validation of GPI biosynthesis as a drug target against African sleeping sickness

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3. Targeting the GPI biosynthetic pathway;Pathogens and Global Health;2018-02-27

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