Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase-Reference-Cited by-同舟云学术

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Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase

Published:2014-03 Issue: Volume:387 Page:54-58
ISSN:0008-6215
Container-title:Carbohydrate Research
language:en
Short-container-title:Carbohydrate Research

Author:

Urbaniak Michael D.,Capes Amy S.,Crossman Arthur,O’Neill Sandra,Thompson Stephen,Gilbert Ian H.,Ferguson Michael A.J.

Funder

Medical Research Council (studentship to ASC) and the Wellcome Trust

Publisher

Elsevier BV

Subject

Organic Chemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference21 articles.

1. Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

2. Cloning of Trypanosoma brucei and Leishmania major Genes Encoding the GlcNAc-Phosphatidylinositol De-N-acetylase of Glycosylphosphatidylinositol Biosynthesis That Is Essential to the African Sleeping Sickness Parasite

3. Essential Roles for GPI-anchored Proteins in African Trypanosomes Revealed Using Mutants Deficient in GPI8

4. Chemical validation of GPI biosynthesis as a drug target against African sleeping sickness

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer;Cell Reports;2024-04

2. Protein lipidation in health and disease: molecular basis, physiological function and pathological implication;Signal Transduction and Targeted Therapy;2024-03-15

3. Inhibiting the GPI Transamidase Subunit GPAA1 Abolishes CD24 Surface Localization and Enhances Macrophage-Mediated Phagocytosis of Ovarian Cancer Cells;2023-10-23

4. N-acetylglucosamine-phosphatidylinositol de-N-acetylase as a novel target for probing potential inhibitor against Leishmania donovani;Journal of Biomolecular Structure and Dynamics;2022-01-11

5. Compounds targeting GPI biosynthesis or N-glycosylation are active against Plasmodium falciparum;Computational and Structural Biotechnology Journal;2022

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