Decatenation checkpoint-defective melanomas are dependent on PI3K for survival

Author:

Brooks Kelly1,Ranall Max1,Spoerri Loredana1,Stevenson Alex1,Gunasingh Gency1,Pavey Sandra1,Meunier Fred2,Gonda Thomas J.1,Gabrielli Brian1

Affiliation:

1. Translational Research Institute; The University of Queensland Diamantina Institute; Brisbane Qld Australia

2. Clem Jones Centre for Ageing Dementia Research; Queensland Brain Institute; The University of Queensland; Brisbane Qld Australia

Funder

National Health and Medical Research Council

Publisher

Wiley

Subject

Dermatology,General Biochemistry, Genetics and Molecular Biology,Oncology

Reference36 articles.

1. Defective Decatenation Checkpoint Function Is a Common Feature of Melanoma;Brooks;J. Invest. Dermatol.,2013

2. G2 arrest in response to topoisomerase II inhibitors: the role of p53;Clifford;Cancer Res.,2003

3. The decatenation checkpoint;Damelin;Br. J. Cancer,2007

4. Mutations of the BRAF gene in human cancer;Davies;Nature,2002

5. A beta version of life: p110beta takes center stage;Dbouk;Oncotarget,2010

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