A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest-Reference-Cited by-同舟云学术

A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest

Published:2018-12-24 Issue:6 Volume:47 Page:2906-2921
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Deiss Katharina¹,Lockwood Nicola¹,Howell Michael²,Segeren Hendrika Alida¹,Saunders Rebecca E²,Chakravarty Probir³,Soliman Tanya N¹,Martini Silvia¹,Rocha Nuno⁴,Semple Robert⁵,Zalmas Lykourgos-Panagiotis⁶,Parker Peter J¹⁷^ORCID

Affiliation:

1. Protein Phosphorylation Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK

2. High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK

3. Bioinformatics, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK

4. The University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge CB2 0QQ, UK

5. The National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK

6. Translational Cancer Therapeutics, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK

7. School of Cancer and Pharmaceutical Sciences King's College London, New Hunt's House, Guy's Campus, London SE1 1UL, UK

Funder

Cancer Research UK

UK Medical Research Council

Wellcome Trust

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/47/6/2906/28312346/gky1295.pdf

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