The giraffe kidney tolerates high arterial blood pressure by high renal interstitial pressure and low glomerular filtration rate

Author:

Damkjaer M.1,Wang T.2,Brøndum E.3,Østergaard K. H.4,Baandrup U.4,Hørlyck A.5,Hasenkam J. M.6,Smerup M.6,Funder J.6,Marcussen N.7,Danielsen C. C.8,Bertelsen M. F.9,Grøndahl C.9,Pedersen M.10,Agger P.10,Candy G.11,Aalkjaer C.312,Bie P.1

Affiliation:

1. Department of Cardiovascular and Renal Research; University of Southern Denmark; Odense Denmark

2. Department of Biological Sciences; Institute of Zoophysiology; Aarhus University; Aarhus Denmark

3. Department of Physiology; Institute of Biomedicine; Aarhus University; Aarhus Denmark

4. Centre for Clinical Research; Hjørring/Department of Clinical Medicine; Aalborg University; Denmark

5. Department of Radiology; Aarhus University Hospital; Aarhus Denmark

6. Department of Cardiothoracic and Vascular Surgery; Institute of Clinical Medicine; Aarhus University Hospital; Aarhus Denmark

7. Department of Clinical Pathology; University of Southern Denmark; Odense Denmark

8. Department of Anatomy; Institute of Biomedicine; Aarhus University; Aarhus Denmark

9. Center for Zoo and Wild Animal Health; Copenhagen Zoo; Copenhagen Denmark

10. MR Research Centre; Institute of Clinical Medicine; Aarhus University Hospital; Aarhus Denmark

11. Department of Physiology and Medicine; University of the Witwatersrand; Johannesburg South Africa

12. Department of Biomedicine; University of Copenhagen; Copenhagen Denmark

Funder

Lundbeckfonden

Carlsbergfondet

Hjerteforeningen

Aase og Ejnar Danielsens Fond

Nyreforeningen

Aarhus University research foundation

Danish Cardiovascular Research Council

Danish Research Council

Fonden til Lægevidenskabens Fremme

The Faculty of Health Science and the Faculty of Natural Sciences

Publisher

Wiley

Subject

Physiology

Reference40 articles.

1. Hypertension and kidney disease: a deadly connection;Barri;Curr Cardiol Rep,2006

2. Jugular venous pooling during lowering of the head affects blood pressure of the anesthetized giraffe;Brondum;Am J Physiol Regul Integr Comp Physiol,2009

3. Comparative cardiovascular physiology: future trends, opportunities and challenges;Burggren;Acta Physiol (Oxf),2014

4. Systemic arterial hemodynamics and the “renal resistive index”: what is in a name?;Chirinos;J Clin Hypertens (Greenwich),2014

5. Low blood volume in the giraffe (Giraffa camelopardalis);Damkjaer;FASEB J,2011

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