Stereochemistry of mephedrone neuropharmacology: enantiomer-specific behavioural and neurochemical effects in rats

Author:

Gregg Ryan A12,Baumann Michael H3,Partilla John S3,Bonano Julie S4,Vouga Alexandre12,Tallarida Christopher S12,Velvadapu Venkata5,Smith Garry R5,Peet M Melissa6,Reitz Allen B5,Negus S Stevens4,Rawls Scott M12

Affiliation:

1. Department of Pharmacology; Temple University School of Medicine; Philadelphia PA USA

2. Center for Substance Abuse Research; Temple University School of Medicine; Philadelphia PA USA

3. Designer Drug Research Unit of the Intramural Research Program; National Institute on Drug Abuse, National Institutes of Health; Baltimore MD USA

4. Department of Pharmacology and Toxicology; Virginia Commonwealth University; Richmond VA USA

5. Fox Chase Chemical Diversity Center Inc.; Doylestown PA USA

6. Department of Psychology; Western Michigan University; Kalamazoo MI USA

Funder

National Institute on Drug Abuse

Publisher

Wiley

Subject

Pharmacology

Reference55 articles.

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2. The Concise Guide to PHARMACOLOGY 2013/14: Transporters;Alexander;Br J Pharmacol,2013b

3. The release of endogenous norepinephrine and dopamine from cerebral cortex by amphetamine;Arnold;J Pharmacol Exp Ther,1977

4. Use of intracranial self-stimulation to evaluate abuse-related and abuse-limiting effects of monoamine releasers in rats;Bauer;Br J Pharmacol,2013

5. The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue;Baumann;Neuropsychopharmacology,2012

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