The natural compound, formononetin, extracted from Astragalus membranaceus increases adipocyte thermogenesis by modulating PPARγ activity

Author:

Nie Tao123ORCID,Zhao Shiting23,Mao Liufeng23,Yang Yiting3,Sun Wei23,Lin Xiaoliang4,Liu Shuo4,Li Kuai23,Sun Yirong23,Li Peng23,Zhou Zhiguang5,Lin Shaoqiang1,Hui Xiaoyan67,Xu Aimin67,Ma Chung Wah4,Xu Yong23,Wang Cunchuan1,Dunbar P Rod8,Wu Donghai239

Affiliation:

1. Central Laboratory of the First Affiliated Hospital of Jinan University; Guangzhou China

2. Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Joint School of Life Sciences; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences; Guangzhou China

3. Guangzhou Medical University; Guangzhou China

4. Research and Development Centre; Infinitus (China) Company Ltd.; Guangzhou China

5. Institute of Metabolism and Endocrinology, 2nd Xiangya Hospital, Central South University, Diabetes Center, Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Diseases; Changsha Hunan China

6. State Key Laboratory of Pharmaceutical Biotechnology; The University of Hong Kong; Hong Kong Hong Kong

7. Department of Medicine; The University of Hong Kong; Hong Kong Hong Kong

8. School of Biological Sciences and Maurice Wilkins Centre; University of Auckland; Auckland New Zealand

9. GUANGZHOU Regenerative Medicine and Health Laboratory; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences; Guangzhou China

Funder

Guangdong Provincial Public interest research and capacity building projects

Science and Technology Planning Project of Guangdong Province

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Chinese Academy of Sciences

the National Basic Research Program of China

Publisher

Wiley

Subject

Pharmacology

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