Methylthioadenosine phosphorylase represents a predictive marker for response to adjuvant interferon therapy in patients with malignant melanoma

Author:

Meyer Stefanie,Wild Peter J.,Vogt Thomas,Bataille Frauke,Ehret Christoph,Gantner Susanne,Landthaler Michael,Klinkhammer-Schalke Monika,Hofstaedter Ferdinand,Bosserhoff Anja K.

Publisher

Wiley

Subject

Dermatology,Molecular Biology,Biochemistry

Reference19 articles.

1. Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumour suppressor region on 9p21;Olopade;Proc Natl Acad Sci USA,1995

2. Methylthioadenosine phosphorylase, a gene frequently codeleted with p16 (cdkN2a/ARF), acts as a tumour suppressor in a breast cancer cell line;Christopher;Cancer Res,2002

3. Methylthioadenosine phosphorylase gene deletions are common in osteosarcoma;Garcia-Castellano;Clin Cancer Res,2002

4. The methylthioadenosine phosphorylase gene is frequently co-deleted with the p16INK4a gene in acute type adult T-cell leukemia;Hori;Int J Cancer,1998

5. Promoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma;Hellerbrand;Carcinogenesis,2006

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