The Oncometabolite 5′-Deoxy-5′-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation-Reference-Cited by-同舟云学术

The Oncometabolite 5′-Deoxy-5′-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation

Published:2020-10-06 Issue: Volume:11 Page:
ISSN:1664-3224
Container-title:Frontiers in Immunology
language:
Short-container-title:Front. Immunol.

Author:

Jacobs Benedikt,Schlögl Sebastian,Strobl Carolin Dorothea,Völkl Simon,Stoll Andrej,Mougiakakos Dimitrios,Malmberg Karl-Johan,Mackensen Andreas,Aigner Michael

Funder

Deutsche Forschungsgemeinschaft

Publisher

Frontiers Media SA

Subject

Immunology,Immunology and Allergy

Reference59 articles.

1. LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells;Brand;Cell Metab.,2016

2. D-2-hydroxyglutarate interferes with HIF-1alpha stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization;Bottcher;Oncoimmunology.,2018

3. The methylthioadenosine phosphorylase gene is frequently co-deleted with the p16INK4a gene in acute type adult T-cell leukemia;Hori;Int J Cancer.,1998

4. Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma;Behrmann;Am J Pathol.,2003

5. Reduced expression of CYLD in human colon and hepatocellular carcinomas;Hellerbrand;Carcinogenesis.,2007

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. HAdV-5 infection dysregulates cysteine, purine, and unsaturated fatty acid metabolism in fibroblasts;2024-06-03

2. Alcohol extract of Rubia yunnanensis: Metabolic alterations and preventive effects against OGD/R‑induced oxidative damage in HT22 cells;Biomedical Reports;2024-03-12

3. Polyamine Inhibitor SAM486A Augments Cytarabine Cytotoxicity in Methylthioadenosine Phosphorylase-deficient Leukemia Cells;Anticancer Research;2024-02-29

4. Metabolic adaptation of NK cell activity and behavior in tumors: challenges and therapeutic opportunities;Trends in Pharmacological Sciences;2023-11

5. Enzyme-mediated depletion of methylthioadenosine restores T cell function in MTAP-deficient tumors and reverses immunotherapy resistance;Cancer Cell;2023-10