Early cell death induced by Clostridium difficile TcdB: Uptake and Rac1-glucosylation kinetics are decisive for cell fate-Reference-Cited by-同舟云学术

Early cell death induced by Clostridium difficile TcdB: Uptake and Rac1-glucosylation kinetics are decisive for cell fate

Published:2018-06-28 Issue:10 Volume:20 Page:e12865
ISSN:1462-5814
Container-title:Cellular Microbiology
language:en
Short-container-title:Cellular Microbiology

Author:

Beer Lara-Antonia¹,Tatge Helma¹,Reich Nicole¹,Tenspolde Michel¹,Olling Alexandra¹,Goy Sebastian¹,Rottner Klemens²³,Alekov Alexi Kirilov⁴,Gerhard Ralf¹^ORCID

Affiliation:

1. Institute of Toxicology; Hannover Medical School; Hannover Germany

2. Division of Molecular Cell Biology; Zoological Institute; Braunschweig Germany

3. Molecular Cell Biology Group; Helmholtz Centre for Infection Research; Braunschweig Germany

4. Institute for Neurophysiology; Hannover Medical School; Hannover Germany

Funder

Federal State of Lower Saxony, Germany, Niedersächsisches Vorab

Publisher

Hindawi Limited

Subject

Virology,Immunology,Microbiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cmi.12865/fullpdf

Reference46 articles.

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4. UDP-glucose deficiency in a mutant cell line protects against glucosyltransferase toxins from Clostridium difficile and Clostridium sordellii;Chaves-Olarte;The Journal of Biological Chemistry,1996

5. R-Ras glucosylation and transient RhoA activation determine the cytopathic effect produced by toxin B variants from toxin A-negative strains of Clostridium difficile;Chaves-Olarte;The Journal of Biological Chemistry,2003

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