The MC 4 receptor agonist RO27‐3225 inhibits NLRP1‐dependent neuronal pyroptosis via the ASK1/JNK/p38 MAPK pathway in a mouse model of intracerebral haemorrhage-Reference-Cited by-同舟云学术

The MC 4 receptor agonist RO27‐3225 inhibits NLRP1‐dependent neuronal pyroptosis via the ASK1/JNK/p38 MAPK pathway in a mouse model of intracerebral haemorrhage

Published:2019-04-09 Issue:9 Volume:176 Page:1341-1356
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Chen Shengpan¹²,Zuo Yuchun²³,Huang Lei²⁴,Sherchan Prativa²,Zhang Jian⁵,Yu Zhengtao¹,Peng Jianhua²⁶,Zhang Junyi²,Zhao Lianhua²,Doycheva Desislava²,Liu Fei³,Zhang John H.²⁴,Xia Ying¹,Tang Jiping²^ORCID

Affiliation:

1. Department of Neurosurgery, Affiliated Haikou Hospital, Xiangya School of MedicineCentral South University Haikou China

2. Department of Physiology, School of MedicineLoma Linda University Loma Linda CA USA

3. Department of Neurosurgery, The Third Xiangya HospitalCentral South University Changsha China

4. Department of AnesthesiologyLoma Linda University Medical Center Loma Linda CA USA

5. School of Traditional Chinese MedicineBeijing University of Chinese Medicine Beijing China

6. Department of NeurosurgeryThe Affiliated Hospital of Southwest Medical University Luzhou China

Funder

National Natural Science Foundation of China

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.14639

Reference62 articles.

1. Inhibition of the Inflammasome Complex Reduces the Inflammatory Response after Thromboembolic Stroke in Mice

2. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors

3. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors

4. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes

5. ASK 1 inhibitor treatment suppresses p38/ JNK signalling with reduced kidney inflammation and fibrosis in rat crescentic glomerulonephritis

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