Inhibition of uridine phosphorylase by pyrimidine nucleoside analogs and consideration of substrate binding to the enzyme based on solution conformation as seen by NMR spectroscopy
Author:
Publisher
Wiley
Subject
Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1432-1033.1988.tb14441.x/fullpdf
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1. Pyrimidine Nucleosidases
2. Thymidine phosphorylase. Substrate specificity for 5-substituted 2'-deoxyuridines
3. Phosphorolysis of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and other 5-substituted-2'-deoxyuridines by purified human thymidine phosphorylase and intact blood platelets
4. Deoxyribosyl exchange reactions leading to the in vivo generation and regeneration of the antiviral agents (E)-5-(2-bromovinyl)-2′-deoxyuridine, 5-ethyl-2′-deoxyuridine and 5-(2-chloroethyl)-2′-deoxyuridine
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2. Substrate Spectra of Nucleoside Phosphorylases and their Potential in the Production of Pharmaceutically Active Compounds;Current Pharmaceutical Design;2018-02-16
3. Uridine phosphorylase in biomedical, structural, and functional aspects: A review;Crystallography Reports;2011-07
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