CYP2B6 Genotype‐Dependent Inhibition of CYP1A2 and Induction of CYP2A6 by the Antiretroviral Drug Efavirenz in Healthy Volunteers-Reference-Cited by-同舟云学术

CYP2B6 Genotype‐Dependent Inhibition of CYP1A2 and Induction of CYP2A6 by the Antiretroviral Drug Efavirenz in Healthy Volunteers

Published:2019-08-12 Issue:6 Volume:12 Page:657-666
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Metzger Ingrid F.¹,Dave Nimita¹²,Kreutz Yvonne¹,Lu Jessica B.L.¹,Galinsky Raymond E.¹³,Desta Zeruesenay¹

Affiliation:

1. Division of Clinical Pharmacology Department of Medicine Indiana University School of Medicine Indianapolis Indiana USA

2. Blueprint Medicines Cambridge Massachusetts USA

3. School of Pharmacy Purdue University West Lafayette Indiana USA

Funder

National Institute of General Medical Sciences

Indiana Clinical and Translational Sciences Institute

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12671

Reference45 articles.

1. Triple-Nucleoside Regimens versus Efavirenz-Containing Regimens for the Initial Treatment of HIV-1 Infection

2. Long-term Safety and Efficacy of a Once-Daily Regimen of Emtricitabine, Didanosine, and Efavirenz in HIV-Infected, Therapy-Naive Children and Adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021

3. Panel on Antiretroviral Guidelines for Adults and Adolescents.Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV. Department of Health and Human Services. . Accessed May 9 2019.

4. Bristol‐Myers Squibb Company 2017.Sustiva (efavirenz) package insert. Bristol‐Myers Squibb Company 1−38 (revised October 2017).

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