A perspective on the physicochemical and biopharmaceutic properties of marketed antiseizure drugs—From phenobarbital to cenobamate and beyond-Reference-Cited by-同舟云学术

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A perspective on the physicochemical and biopharmaceutic properties of marketed antiseizure drugs—From phenobarbital to cenobamate and beyond

Published:2020-07-02 Issue:8 Volume:61 Page:1543-1552
ISSN:0013-9580
Container-title:Epilepsia
language:en
Short-container-title:Epilepsia

Author:

Odi Reem¹,Bibi David¹,Wager Travis²,Bialer Meir¹³^ORCID

Affiliation:

1. Faculty of Medicine School of Pharmacy Institute of Drug Research Hebrew University of Jerusalem Jerusalem Israel

2. Rgenta Therapeutics LabCentral Cambridge Massachusetts USA

3. Affiliated with David R. Bloom Center for Pharmacy Hebrew University of Jerusalem Jerusalem Israel

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/epi.16597

Reference33 articles.

1. The State of Innovation in Drug Development

2. New avenues for anti‐epileptic drug discovery and development;Loscher W;Nat Rev,2013

3. Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety

4. Analysing molecular polar surface descriptors to predict blood-brain barrier permeation

5. Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development

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