Pretreatment HIV drug resistance predicts accumulation of new mutations in ART‐naïve Ugandan children

Author:

Soeria‐Atmadja Sandra12ORCID,Amuge Pauline3,Nanzigu Sarah4,Bbuye Dickson3,Rubin Johanna1,Eriksen Jaran56,Kekitiinwa Adeodata3,Obua Celestino7,Gustafsson Lars L.5,Navér Lars12ORCID

Affiliation:

1. Department of Clinical Science, Intervention and Technology Division of Paediatrics Karolinska Institutet Stockholm Sweden

2. Department of Paediatrics Karolinska University Hospital Stockholm Sweden

3. Baylor College of Medicine Children’s Foundation‐Uganda Kampala Uganda

4. Department of Clinical Pharmacology & Therapeutics Makerere University Kampala Uganda

5. Department of Laboratory Science Division of Clinical Pharmacology Karolinska Institutet Stockholm Sweden

6. Department of Public Health Karolinska Institutet Stockholm Sweden

7. College of Health Sciences Mbarara University of Science and Technology Mbarara Uganda

Publisher

Wiley

Subject

General Medicine,Pediatrics, Perinatology, and Child Health

Reference34 articles.

1. UNAIDS.Global HIV & AIDS statistics — 2018 fact sheet.http://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf. Accessed May 7 2019.

2. World Health Organization.HIV drug resistance report 2017.http://www.who.int/hiv/pub/drugresistance/hivdr‐report‐2017/en/. Accessed 20 Nov 2017.

3. HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis

4. Antiretroviral Resistance Patterns in Children with HIV Infection

5. Alarming increase in pretreatment HIV drug resistance in children living in sub-Saharan Africa: a systematic review and meta-analysis

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