Prevalence of suspected obesity hypoventilation syndrome in Hungarian Intensive Care Units during the COVID‐19 pandemic

Author:

Baglyas Szabolcs1ORCID,Valkó Luca1,Donka Dániel2,Fodor Gábor3,Hansági Edit4,Méhész István5,Gál János1,Lorx András1

Affiliation:

1. Department of Anesthesiology and Intensive Care Semmelweis University Budapest Hungary

2. Department of Anesthesiology, Intensive Care and Emergency Medicine Bajcsy‐Zsilinszky Hospital Budapest Hungary

3. Central Department of Anesthesiology and Intensive Care Petz Aladár County Teaching Hospital Győr Hungary

4. Department of Anesthesiology and Intensive Care Saint Barbara County Hospital Tatabánya Hungary

5. Central Department of Anesthesiology and Intensive Care Uzsoki Street Hospital Budapest Hungary

Abstract

AbstractIntroductionThe symptoms of obesity hypoventilation syndrome (OHS) may be present for years with concomitant progressive comorbidities, and the condition is frequently diagnosed late as a result of acute‐on‐chronic hypercapnic respiratory failure. Although some data exist on intensive care unit (ICU) prevalence, mortality and morbidity of OHS, little is known about the ICU mortality of these chronic respiratory failure patients during the COVID‐19 pandemic.MethodsWe performed a cross‐sectional observational study in five Hungarian Intensive Care Units for 4 months during the COVID‐19 pandemic. All ICU patients were screened for OHS risk factors by treating physicians. Risk factors were defined as obesity (body mass index [BMI] ≥ 30 kg/m2) and at least one of the following: Epworth Sleepiness Score ≥ 6; symptoms of right heart failure; daytime or night‐time hypoxemia; presence of loud snoring; witnessed apnoea. We calculated prevalence, mortality and factors associated with unfavourable outcome.ResultsA total of 904 ICU patients were screened for OHS risk factors. Overall 79 (8.74 ± 5.53%) patients were reported to have met the criteria for suspected OHS with a mortality rate of 40.5%; 69% (54 patients) of the cohort displayed at least 3 symptoms related to OHS before their acute illness. COVID‐19 infection was associated with higher mortality in OHS‐suspected patients, independently of actual BMI.ConclusionDespite the increased risk of obese patients, suspected OHS did not show higher prevalence than expected during the COVID‐19 pandemic in critically ill patients. COVID‐19 infection however was a risk for mortality in these patients, independent of actual BMI.

Publisher

Wiley

Subject

Genetics (clinical),Pulmonary and Respiratory Medicine,Immunology and Allergy

Reference27 articles.

1. Obesity hypoventilation syndrome: a state‐of‐the‐art review;Mokhlesi B;Respir Care,2010

2. Acute ventilatory failure complicating obesity hypoventilation: update on a ‘critical care syndrome’

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