Novel transforming growth factor beta receptor I kinase inhibitor galunisertib (LY2157299) in advanced hepatocellular carcinoma

Author:

Faivre Sandrine1,Santoro Armando2,Kelley Robin K.3,Gane Ed4,Costentin Charlotte E.5ORCID,Gueorguieva Ivelina6,Smith Claire6,Cleverly Ann6,Lahn Michael M.7,Raymond Eric8,Benhadji Karim A.7,Giannelli Gianluigi9

Affiliation:

1. Oncologie Médicale Hopital Beaujon Clichy France

2. Istituto Clinico Humanitas Humanitas University Rozzano Italy

3. University of California San Francisco CA

4. Auckland City Hospital Auckland New Zealand

5. Hospital Henri Mondor Creteil France

6. Lilly Research Centre Erl Wood Manor Windlesham UK

7. Eli Lilly and Company Indianapolis IN

8. Centre Hospitalier Paris Saint‐Joseph Paris France

9. National Institute of Gastroenterology Research Instituts “S. De Bellis” Research Hospital, Castellana Grotte Bari Italy

Funder

Eli Lilly and Company

Publisher

Wiley

Subject

Hepatology

Reference35 articles.

1. Epidemiology of Hepatocellular Carcinoma

2. Hepatocellular Carcinoma: Therapeutic Guidelines and Medical Treatment

3. Sorafenib in Advanced Hepatocellular Carcinoma

4. Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial

5. Final analysis of GIDEON (Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma [HCC] and of its treatment with sorafenib [Sor]) in >3000 Sor‐treated patients (pts): clinical findings in pts with liver dysfunction. 2013 ASCO Annual Meeting, 2013. Chicago;Marrero JA;ASCOJ Clin Oncol,2013

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