Author:
Dimitroulis Dimitrios,Damaskos Christos,Garmpis Nikolaos,Garmpi Anna
Abstract
Hepatocellular carcinoma (HCC) ranks among the most prevalent cancers globally, claiming the third spot in cancer-related fatalities. Surgery stands out as the optimal prognostic measure. Notable factors contributing to HCC encompass chronic viral infections, specifically hepatitis B virus (HBV) and hepatitis C virus (HCV), aflatoxins, tobacco use, and non-alcoholic fatty liver disease (NAFLD). The imperative task at hand is the creation of effective molecular markers and alternative therapeutic targets of substantial importance. This chapter delves into the overarching characteristics of HCC, offering insights into various targeted therapies that have propelled advancements in HCC treatment, underscoring the critical need for ongoing developments in this direction.