Transcriptomic landscape profiling of metformin‐treated healthy mice: Implication for potential hypertension risk when prophylactically used-Reference-Cited by-同舟云学术

Transcriptomic landscape profiling of metformin‐treated healthy mice: Implication for potential hypertension risk when prophylactically used

Published:2020-06-11 Issue:14 Volume:24 Page:8138-8150
ISSN:1582-1838
Container-title:Journal of Cellular and Molecular Medicine
language:en
Short-container-title:J Cell Mol Med

Author:

Meng Yuhong¹,Xiang Rui¹,Yan Han¹,Zhou Yiran¹,Hu Yuntao¹,Yang Jichun¹,Zhou Yuan¹^ORCID,Cui Qinghua¹

Affiliation:

1. Department of Physiology and Pathophysiology Department of Biomedical Informatics Center for Non‐coding RNA Medicine MOE Key Lab of Cardiovascular Sciences School of Basic Medical Sciences Peking University Beijing China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.15472

Reference64 articles.

1. Metformin—mode of action and clinical implications for diabetes and cancer

2. Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

3. AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

4. Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

5. Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo

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