Affiliation:
1. School of Biology and Biological Engineering South China University of Technology Guangzhou China
2. Guangdong Provincial Key Laboratory of Fermentation and Enzyme Engineering South China University of Technology Guangzhou China
3. State Key Laboratory of Pulp and Paper Engineering South China University of Technology Guangzhou China
Abstract
AbstractButyl butyrate is a short‐chain fatty acid ester (C8) with a fruity aroma. It has broad prospects in the fields of foods, cosmetics and biofuels. At present, butyl butyrate is produced by chemical synthesis in the industry, but it is highly dependent on petroleum‐based products. The growing concerns regarding the future scarcity of fossil fuels have been strongly promoted the transition from traditional fossil fuels and products to renewable bioenergy and biochemicals. Therefore, it is necessary to develop a green biochemical technology to replace traditional petroleum‐based materials. In recent years, microorganisms such as Escherichia coli and Clostridium have been engineered to serve as cell factories for the sustainable one‐pot production of short‐chain fatty acid esters, including butyl butyrate. This opinion highlights the recent development in the use of lipases and alcohol acyltransferases (AATs) for butyl butyrate production in microbial fermentation, as well as future perspectives.
Funder
Fundamental Research Funds for the Central Universities
National Natural Science Foundation of China