A metabolomic analysis of thiol response for standard and modified N ‐acetyl cysteine treatment regimens in patients with acetaminophen overdose-Reference-Cited by-同舟云学术

A metabolomic analysis of thiol response for standard and modified N ‐acetyl cysteine treatment regimens in patients with acetaminophen overdose

Published:2021-04-09 Issue:4 Volume:14 Page:1476-1489
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Dear James W¹,Ng Mei Li²³⁴,Bateman D. Nicholas¹,Leroy Sivappiragasam Pakkiri²,Choi Hyungwon²³⁵,Khoo Benjamin Bing Jie²³,Ibrahim Baharudin⁶,Drum Chester Lee²³⁷⁸

Affiliation:

1. Pharmacology, Toxicology, and Therapeutics Centre for Cardiovascular Science University of Edinburgh Edinburgh UK

2. Cardiovascular Research Institute National University Health System Singapore City Singapore

3. Department of Medicine Yong Loo Lin School of Medicine National University of Singapore Singapore City Singapore

4. Advanced Medical and Dental Institute Universiti Sains Malaysia Kepala Batas Malaysia

5. Institute of Molecular and Cell Biology Agency for Science, Technology, and Research Singapore City Singapore

6. School of Pharmaceutical Sciences Universiti Sains Malaysia Kepala Batas Malaysia

7. Department of Surgery Yong Loo Lin School of Medicine National University of Singapore Singapore City Singapore

8. Department of Biochemistry Yong Loo Lin School of Medicine National University of Singapore Singapore City Singapore

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.13009

Reference38 articles.

1. Apoptosis and necrosis in liver disease

2. Acetylcysteine for Acetaminophen Poisoning

3. Mechanisms of acetaminophen-induced liver injury and its implications for therapeutic interventions

4. Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial

5. Safety and Efficacy of the SNAP 12-hour Acetylcysteine Regimen for the Treatment of Paracetamol Overdose

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