Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites-Reference-Cited by-同舟云学术

Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites

Published:2023 Issue:20 Volume:14 Page:5291-5301
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kaur Amanpreet¹^ORCID,Lin Weifeng¹^ORCID,Dovhalyuk Vladyslav¹^ORCID,Driutti Léna¹,Di Martino Maria Letizia²^ORCID,Vujasinovic Miroslav³,Löhr J.-Matthias³⁴,Sellin Mikael E.²^ORCID,Globisch Daniel¹^ORCID

Affiliation:

1. Department of Chemistry – BMC, Science for Life Laboratory, Uppsala University, 75124, Uppsala, Sweden

2. Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, 75123, Uppsala, Sweden

3. Department for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden

4. Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden

Abstract

Thiol-containing metabolites in all organisms are involved in the regulation of diverse biological processes. We have developed a new method comprising bicyclobutane for chemoselective capturing and mass spectrometric analysis of this compound class.

Funder

Vetenskapsrådet

Swedish Cancer Foundation

Science for Life Laboratory

Stiftelsen för Strategisk Forskning

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC00224A

Reference75 articles.