Daylight photodynamic therapy with methyl aminolevulinate cream is effective and nearly painless in treating actinic keratoses: a randomised, investigator-blinded, controlled, phase III study throughout Europe

Author:

Lacour J-P.1,Ulrich C.2,Gilaberte Y.3,Von Felbert V.4,Basset-Seguin N.5,Dreno B.6,Girard C.7,Redondo P.8,Serra-Guillen C.9,Synnerstad I.10,Tarstedt M.11,Tsianakas A.12,Venema A.W.13,Kelleners-Smeets N.14,Adamski H.15,Perez-Garcia B.16,Gerritsen M.J.17,Leclerc S.18,Kerrouche N.18,Szeimies R-M.19

Affiliation:

1. Department of Dermatology; Hôpital Archet2, University Hospital of Nice; Nice France

2. Charité Campus Mitte; Universitätsmedizin Berlin; Klinik für Dermatologie; Venerologie und Allergologie Hautturmorcentrum der Charité (HTCC); Berlin Germany

3. Hospital San Jorge; Huesca Spain

4. Department of Dermatology; University Hospital; RWTH Aachen University; Aachen Germany

5. Saint-Louis Hospital; Paris France

6. CHU Hotel Dieu; Nantes Cedex 1 France

7. Department of Dermatology; Hospital Saint Eloi; Montpellier France

8. Department of Dermatology; University Clinic of Navarra; Pamplona Spain

9. Instituto Valenciano de Oncologia; Valencia Spain

10. Hudmottagningen; Norrköping Sweden

11. Department of Dermatology; Karlskoga Hospital; Karlskoga Sweden

12. Department of Dermatology; University Hospital of Münster; Münster Germany

13. Wilhelmina Ziekenhuis Assen; Assen The Netherlands

14. Dermatology Department; Maastricht University Medical Centre; Maastricht The Netherlands

15. Dermatology Department; Pontchaillou Hospital; Rennes France

16. Hospital Ramón y Cajal; Servicio de Dermatología; Carretera de Colmenar Viejo; Madrid Spain

17. Radboud University Medical Center; Nijmegen The Netherlands

18. Galderma R&D; Sophia Antipolis France

19. Klinik für Dermatologie und Allergologie; Klinikum Vest GmbH; Behandlungszentrum Knappschaftskrankenhaus; Recklinghausen Germany

Funder

Galderma R&D

Publisher

Wiley

Subject

Infectious Diseases,Dermatology

Reference26 articles.

1. Prevalence of solar damage and actinic keratosis in a Merseyside population;Memon;Br J Dermatol,2000

2. Prevalence of actinic keratosis and its risk factors in the general population: the Rotterdam Study;Flohil;J Invest Dermatol,2013

3. Solar keratosis: epidemiology, pathogenesis, presentation and treatment;Holmes;Australas J Dermatol,2007

4. Current evidence and applications of photodynamic therapy in dermatology;Wan;Clin Cosmet Investig Dermatol,2014

5. Stockfleth E Actinic Keratosis and Field Cancerization: New Insights. Medscape 2012 http://www.medscape.org/viewarticle/774743

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