The impact of MK-467 on plasma drug concentrations, sedation and cardiopulmonary changes in sheep treated with intramuscular medetomidine and atipamezole for reversal-Reference-Cited by-同舟云学术

The impact of MK-467 on plasma drug concentrations, sedation and cardiopulmonary changes in sheep treated with intramuscular medetomidine and atipamezole for reversal

Published:2018-01-19 Issue:3 Volume:41 Page:447-456
ISSN:0140-7783
Container-title:Journal of Veterinary Pharmacology and Therapeutics
language:en
Short-container-title:J vet Pharmacol Therap

Author:

Adam M.¹²^ORCID,Raekallio M. R.¹,Keskitalo T.¹,Honkavaara J. M.¹,Scheinin M.³⁴,Kajula M.⁵,Mölsä S.¹,Vainio O. M.¹^ORCID

Affiliation:

1. Department of Equine and Small Animal Medicine; Faculty of Veterinary Medicine; University of Helsinki; Helsinki Finland

2. Pharmacology Department; Faculty of Veterinary Medicine; Beni-Suef University; Beni-Suef Egypt

3. Department of Pharmacology; Drug Development and Therapeutics; University of Turku; Turku Finland

4. Unit of Clinical Pharmacology; Turku University Hospital; Turku Finland

5. Admescope Ltd.; Oulu Finland

Funder

Vetcare Ltd., Finland

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jvp.12486/fullpdf

Reference44 articles.

1. Adam , M. Salla , K. M. Raekallio , M. R. Honkavaara , J. M. Mölsä , S. Vainio , O. M. 2016 Cardiopulmonary effects of MK-467, a peripheral alpha 2 -adrenoceptor antagonist, in sheep receiving medetomidine-ketamine Proceedings of the Association of Veterinary Anaesthetists Autumn Meeting 79 Prague, Czech Republic

2. Influence of drugs on the response characteristics of the LiDCO sensor: And in vitro study;Ambrisko;British Journal of Anaesthesia,2013

3. Effects of MK-467 on the antinociceptive and sedative actions and pharmacokinetics of medetomidine in dogs;Bennett;Journal of Veterinary Pharmacology and Therapeutics,2016

4. Effects of the α2-adrenoceptor agonist medetomidine on the distribution and clearance of alfaxalone during coadministration by constant rate infusion in dogs;Bennett;American Journal of Veterinary Research,2017

5. Hemodynamic and sedative effects of dexmedetomidine in dog;Bloor;The Journal of Pharmacology and Experimental Therapeutics,1992

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