A high‐fat diet rich in corn oil induces cardiac fibrosis in rats by activating JAK2/STAT3 and subsequent activation of ANG II/TGF‐1β/Smad3 pathway: The role of ROS and IL‐6 trans‐signaling-Reference-Cited by-同舟云学术

A high‐fat diet rich in corn oil induces cardiac fibrosis in rats by activating JAK2/STAT3 and subsequent activation of ANG II/TGF‐1β/Smad3 pathway: The role of ROS and IL‐6 trans‐signaling

Published:2019-06-20 Issue:8 Volume:43 Page:
ISSN:0145-8884
Container-title:Journal of Food Biochemistry
language:en
Short-container-title:J Food Biochem

Author:

Eid Refaat A.¹^ORCID,Alkhateeb Mahmoud A.²,El‐Kott Attalla Farag³⁴,Eleawa Samy M.⁵,Zaki Mohamed Samir Ahmed⁶⁷,Alaboodi Sultan Abdullah⁸,Salem Al‐Shudiefat Abd Al‐Rahman⁹,Aldera Hussain²¹⁰,Alnamar Nada Mohammad¹¹,Alassiri Mohammed²¹⁰,Khalil Mohammad A.¹²

Affiliation:

1. Department of Clinica Pathology and Anatomy, College of Medicine King Khalid University (KKU) Abha Kingdom of Saudi Arabia

2. Basic Medical Sciences (Physiology Section), College of Medicine King Saud bin Abdulaziz University for Health Sciences (KSAU‐HS) Riyadh Kingdom of Saudi Arabia

3. Department of Biology, College of Science King Khalid University (KKU) Abha Kingdom of Saudi Arabia

4. Department of Zoology, Faculty of Science Damanhour University Damanhour Egypt

5. Department of Applied Medical Sciences, College of Health Sciences PAAET Safat Kuwait

6. Department of Anatomy, College of Medicine King Khalid University (KKU) Abha Kingdom of Saudi Arabia

7. Department of Histology, Faculty of Medicine Zagazig University Zagazig Egypt

8. Central laboratories, Huraymala General Hospital, Ministry of Health Riyadh Kingdom of Saudi Arabia

9. Department of Medical Laboratory Sciences the Hashemite University Zarqa Jordan

10. King Abdullah International Medical Research Center Riyadh Kingdom of Saudi Arabia

11. Khamis Mushait General Hospital, Ministry of Health Abha Kingdom of Saudi Arabia

12. Department of Basic Medical Sciences, College of MedicineKing Fahid Medical City (KFMC) Riyadh Kingdom of Saudi Arabia

Funder

King Khalid University

Publisher

Wiley

Subject

Cell Biology,Pharmacology,Food Science,Biophysics

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jfbc.12952

Reference66 articles.

1. Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation

2. Metformin Inhibits Angiotensin II-Induced Differentiation of Cardiac Fibroblasts into Myofibroblasts

3. Linoleic Acid Augments Oxidative Damage and Initiates Fibrosis in Cardiomyocytes and Fibroblasts

4. Excess Linoleic Acid Increases Collagen I/III Ratio and “Stiffens” the Heart Muscle Following High Fat Diets

5. The myocardial JAK/STAT pathway: From protection to failure

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