Rho kinase inhibition drives megakaryocyte polyploidization and proplatelet formation throughMYCandNFE2downregulation
Author:
Affiliation:
1. Platelet Biology Laboratory; Lindsley F. Kimball Research Institute; New York Blood Center; New York NY USA
2. Cellular Therapy Laboratory; Hematology Division; Santa Casa Medical School; São Paulo Brazil
Funder
F. M. Kirby Foundation
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjh.12709/fullpdf
Reference31 articles.
1. Optimizing megakaryocyte polyploidization by targeting multiple pathways of cytokinesis;Avanzi;Transfusion,2012
2. Proplatelet formation is regulated by the Rho/ROCK pathway;Chang;Blood,2007
3. Regulation of c-myc expression by PDGF through Rho GTPases;Chiariello;Nature Cell Biology,2001
4. Megakaryocyte development and platelet production;Deutsch;British Journal of Haematology,2006
5. Mimicking the haematopoietic niche microenvironment provides a novel strategy for expansion of haematopoietic and megakaryocyte-progenitor cells from cord blood;Deutsch;British Journal of Haematology,2010
Cited by 30 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Mass production of iPSC-derived platelets toward the clinical application;Regenerative Therapy;2024-03
2. Multiphoton In Vivo Microscopy of Embryonic Thrombopoiesis Reveals the Generation of Platelets through Budding;Cells;2023-10-06
3. Fasudil promotes polyploidization of megakaryoblasts in an acute megakaryocyte leukemia model;Naunyn-Schmiedeberg's Archives of Pharmacology;2023-05-10
4. Engineered cord blood megakaryocytes evade killing by allogeneic T-cells for refractory thrombocytopenia;Frontiers in Immunology;2022-09-20
5. Understanding Aberrant Signaling to Elude Therapy Escape Mechanisms in Myeloproliferative Neoplasms;Cancers;2022-02-15
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3