Mechanistic Model for Blood Pressure and Heart Rate Changes Produced by Telmisartan in Human Beings
Author:
Affiliation:
1. Department of Pharmacology; Yonsei University College of Medicine; Seoul Korea
2. Brain Korea 21 Plus Project for Medical Science; Yonsei University; Seoul Korea
Funder
Brain Korea 21 PLUS Project for Medical Science, Yonsei University
Publisher
Wiley
Subject
Pharmacology,Toxicology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12856/fullpdf
Reference24 articles.
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2. In vitro and in vivo characterization of the activity of telmisartan: an insurmountable angiotensin II receptor antagonist;Maillard;J Pharmacol Experiment Therap,2002
3. Population pharmacokinetics of an angiotensin II receptor antagonist, telmisartan, in healthy volunteers and hypertensive patients;Tatami;Drug Metab Pharmacokinet,2003
4. Pharmacokinetic-pharmacodynamic modeling of telmisartan using an indirect response model in spontaneously hypertensive rats;Hao;Acta Pharmacol Sin,2007
5. Pharmacokinetic-pharmacodynamic (PK-PD) modeling of cardiovascular effects of metoprolol in spontaneously hypertensive rats: a microdialysis study;Hocht;Naunyn-Schmiedeberg's Arch Pharmacol,2006
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