Androgen actions in mouse wound healing: Minimal in vivo effects of local antiandrogen delivery

Author:

Wang Yiwei1,Simanainen Ulla1,Cheer Kenny1,Suarez Francia G.1,Gao Yan Ru1,Li Zhe12,Handelsman David1,Maitz Peter12

Affiliation:

1. Burns and Reconstructive Surgery Unit, Burns Research Group and Andrology Group, ANZAC Research Institute, University of Sydney; Concord Australia

2. Burns and Reconstructive Surgery Unit; Burns Research Group and Andrology Group, Concord Repatriation General Hospital; Concord Australia

Funder

Australian National Health and Medical Research Council

Publisher

Wiley

Subject

Dermatology,Surgery

Reference40 articles.

1. CRC 2012 http://www.woundcrc.com

2. Androgen receptor-mediated inhibition of cutaneous wound healing;Ashcroft;J Clin Invest,2002

3. Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-α expression;Lai;J Clin Invest,2009

4. Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking β-catenin nuclear translocation and cross-talk with TGF-β signaling in keratinocytes;Toraldo;Wound Repair Regen,2012

5. Predominant expression of 5 alpha-reductase type 1 in public skin from normal subjects and hirsute patients;Mestayer;J Clin Endocrinol Metab,1996

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