Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking β-catenin nuclear translocation and cross-talk with TGF-β signaling in keratinocytes
Author:
Affiliation:
1. Section of Endocrinology, Diabetes, and Nutrition; Boston University School of Medicine; Boston; Massachusetts
2. Dermatopathology Section, Department of Dermatology; Boston University School of Medicine; Boston; Massachusetts
Publisher
Wiley
Subject
Dermatology,Surgery
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1524-475X.2011.00757.x/fullpdf
Reference41 articles.
1. A review of gene and stem cell therapy in cutaneous wound healing;Branski;Burns,2009
2. Human skin wounds: a major and snowballing threat to public health and the economy;Sen;Wound Rep Regen,2009
3. Estrogen accelerates cutaneous wound healing associated with an increase in TGF-beta1 levels;Ashcroft;Nat Med,1997
4. Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor;Ashcroft;J Clin Invest,2003
5. Androgens modulate the inflammatory response during acute wound healing;Gilliver;J Cell Sci,2006
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