Protective effect of acetyl-l-carnitine against cisplatin ototoxicity: role of apoptosis-related genes and pro-inflammatory cytokines

Author:

Altun Z.1,Olgun Y.2,Ercetin P.1,Aktas S.1,Kirkim G.2,Serbetcioglu B.2,Olgun N.3,Guneri E. A.2

Affiliation:

1. Department of Basic Oncology; Institute of Oncology, Dokuz Eylul University; Izmir 35340 Turkey

2. Department of Otolaryngology Head and Neck Surgery; Dokuz Eylul University Faculty of Medicine; Izmir 35340 Turkey

3. Department of Pediatric Oncology; Dokuz Eylul University Institute of Oncology; Izmir 35340 Turkey

Publisher

Wiley

Subject

Cell Biology,General Medicine

Reference42 articles.

1. Cisplatin ototoxicity and protection: clinical and experimental studies;Rybak;Tohoku J. Exp. Med.,2009

2. Selective GSK-3beta inhibitors attenuate the cisplatin-induced cytotoxicity of auditory cells;Park;Hear. Res.,2009

3. Establishment and characterization of conditionally immortalized organ of corti cell lines;Kalinec;Cell Biol. Int.,1999

4. Carnitine and its role in fatty acid metabolism;Fritz;Adv. Lipid Res.,1963

5. New genetic defects in mitochondrial fatty acid oxidation and carnitine deficiency;Stanley;Adv. Pediatr.,1987

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