Validation of soluble amyloid-β precursor protein assays as diagnostic CSF biomarkers for neurodegenerative diseases

Author:

van Waalwijk van Doorn Linda J.C.1,Koel-Simmelink Marleen J.2,Haußmann Ute3,Klafki Hans34,Struyfs Hanne5,Linning Philipp6,Knölker Hans-Joachim6,Twaalfhoven Harry2,Kuiperij H. Bea1,Engelborghs Sebastiaan57,Scheltens Philip8,Verbeek Marcel M.1,Vanmechelen Eugeen9,Wiltfang Jens4,Teunissen Charlotte E.2

Affiliation:

1. Department of Neurology; Department of Laboratory Medicine; Radboud University Medical Center; Radboud Alzheimer Centre; Donders Institute for Brain, Cognition and Behaviour; Nijmegen The Netherlands

2. Neurochemistry Laboratory and Biobank; Department of Clinical Chemistry; VU University Medical Center; Amsterdam The Netherlands

3. Department of Psychiatry and Psychotherapy; Faculty of Medicine; LVR-Hospital Essen; University of Duisburg-Essen; Essen Germany

4. Department of Psychiatry and Psychotherapy; University Medical Center Goettingen; Georg-August-University; Goettingen Germany

5. Reference Center for Biological Markers of Dementia (BIODEM); Institute Born-Bunge; University of Antwerp; Antwerp Belgium

6. Department of Chemistry; Technische Universität Dresden; Dresden Germany

7. Memory Clinic and Department of Neurology; Hospital Network Antwerp (ZNA); Antwerp Belgium

8. Alzheimer Center VUmc; Amsterdam The Netherlands

9. R&D; ADx NeuroSciences; Ghent Belgium

Funder

BIOMARKAPD

ZonMw

Flanders Impulse Program on Networks for Dementia Research

Bundesministerium für Bildung und Forschung

Protein Research Unit Ruhr within Europe

University of Antwerp Research Fund

Alzheimer Research Foundation

Agentschap voor Innovatie door Wetenschap en Technologie

Fonds Wetenschappelijk Onderzoek

Belgian Science Policy Office Interuniversity Attraction Poles (IAP) program

Flemish Government initiated Methusalem excellence grant

CAVIA project

ADx Neurosciences

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

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